A 45-year-old male presents to the clinic with fatigue, unexplained bruising, and frequent nosebleeds. Blood tests reveal leukocytosis, anemia, and thrombocytopenia. A bone marrow biopsy confirms the diagnosis of acute myelogenous leukemia (AML). Answer all questions listed below and cite evidence-based sources to support your initial post and responses.
Which genetic mutations are commonly associated with the disease?
Why is the patient presenting with the specific symptoms described?
Discuss the pathophysiological mechanisms of the disease in detail.
What do the blood test results tell us about the disease and disease progression?